Skip to Content

Clinical Trials

NIH Establishes National Research Study Recruitment Registry
A nationwide registry has been created to match volunteers with researchers. ResearchMatch.org is a secure, user-friendly web site that is complementary to Clinicaltrials.gov. ResearchMatch will match individuals in the US with researchers who are approved to recruit volunteers. Researchers affiliated with participating Clinical and Translational Science Awards (CTSAs) institutions may use the web site during the first year of the project.

Clinical trials

Clinical trial participation is an individual, and important, decision. Clinical trials are designed to test new medications in people. Clinical trials may involve a placebo group (inactive ‘medicine’) to see if the new medication offers an advantage over current standard treatment. Some trials are ‘open label’, in which all participants receive active medications or experimental treatment.

There are many advantages to participating in clinical trials. Participants in clinical trials at a minimum receive current standard care for their disease from medical teams experienced with the disease. Clinical trials also offer the opportunity to try a new medication long before it is approved by the Food and Drug Administration.

If you choose to participate in a clinical trial, you have the right to understand fully what is expected of you, what the trial will involve and the potential risks to your health. You also have the right to withdraw your consent to participate at any time. Learn more about clinical trials, including those listed on this page, at www.clinicaltrials.gov.

The clinical trials listed here were verified as open and enrolling at the time the post was made, and are monitored periodically to ensure that the trial is still accepting participants. If a trial is no longer accepting patients, APFED may not be notified. If you find that registration has closed for a trial that is still listed on this page, please notify mail@apfed.org.

Trials That May be of Interest to Our Members
Updated 8/22/14

 

Eosinophilic Colitis (EC)

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

Study Reference: NCT00267501
Location: Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Learn more


Eosinophilic Esophagitis (EoE)

Anti-IL-13 antibody (RPC4046) drug in Adults with EOE: A Phase II, Multi-Center, Multi-National,  Randomized, Double-Blind, Placebo Controlled, Parallel Group Study

Study Reference: NCT02098473
Location: Please view the link below for the complete list of locations.
Learn more

Cytosponge Protocol

Study Reference: NCT01585103
Location: Mayo Clinic, Rochester MN
Learn more

Data and Sample Collection Study to Elucidat the Mechanisms of Eosinophilic Disorders

Study Reference: NCT00267501
Location: Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Learn more

Esophageal String Test in Eosinophilic Esophagitis

Study Reference: NCT02008903
Location: Children's Hospital Colorado (Aurora, CO); Lurie Children's Hospital (Chicago, IL); Northwestern University (Chicago, IL)
Learn more

Eosinophilic Esophagitis Clinical Therapy Trial

Study Reference: NCT01821898
Location: Texas Children's Hospital, Houston, TX
Learn more

Eosinophilic Esophagitis Databank

Study Reference: NCT01323803
Location: Please view the link for the complete list of locations.
Learn more

Confocal Laser Endomicroscopy in Patients with Eosinophilic Esophagitis

Study Reference: NCT01234376
Location: University of Erlangen-Nuremberg, Erlangen, Bayern, Germany
Learn more

Development, Validation and Evaluation of an Adult and Pediatric Eosinophilic Esophagitis Activity Index (EEsAI)

Study Reference: NCT00939263
Location: Please view the link below for the complete list of locations.
Learn more

Dietetic Versus Topical Steroids for Pediatric Eosinophilic Esophagitis

         Study Reference: NCT01846962
         Location
: Rome, Italy
         Learn more

Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders

Study Reference: NCT01212016
Location: NIH, Bethesda, MD
Learn more

Intestinal Permeability in Response to Treatment in Eosinophilic Esophagitis Patients

          Study Reference: NCT01641913
          Location
: Mayo Clinic, Rochester MN
          Learn more

Molecular Basis of Food Allergy

       Study Reference: 01832324
       Location: Children's Hospital of Philadelphia
       Learn more

Mucosal Impedance and Eosinophilic Esophagitis

         Study Reference: NCT01953575
         Location: Mayo Clinic, Rochester MN
         Learn more

Nasal Nitric Oxide Levels in EoE

         Study Reference: NCT01929824
         Location: Mayo Clinic, Rochester MN
        
Learn more

OBS (Oral Budesonide Suspension) in Adolescent and Young Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension

Study Reference: NCT01642212
Location: Please view the link below for the complete list of locations.
Learn more

Prevalence of Food Allergies in a Cohort of Adult Patients With Eosinophilic Esophagitis

Study Reference: NCT01631591
Location: University of South Florida, Tampa, FL   
Learn more

Risk Factors and Biomarkers for Diagnosis and Treatment of EoE

Study Reference: NCT01988285
Location: University of North Carolina, Chapel Hill NC  
Learn more

Sirolimus in Eosinophilic GI Disease

Study Reference: NCT01814059
Location: National Institutes of Health Clinical Center, Bethesda, MD
Learn more

Study of the Efficiency of Esophageal Dilation on Patient With Eosinophilic Esophagitis (EOE)

Study Reference: NCT00880906
Location:  Vanderbilt University Medical Center Department of Gastroenterology, Nashville, TN
Learn more

Testing Effectiveness of Losartan vs Placebo in Patients With EoE With or Without a CTD

Study reference: NCT01808196
Location: Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Learn more

Trial of Montelukast in Eosinophilic Esophagitis

Study Reference: NCT00511316
Location: Mayo Clinic, Rochester, MN
Learn more


Eosinophilic Gastroenteritis (EGE)

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

Study Reference: NCT00267501
Location: Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Learn more

Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders

Study Reference: NCT01212016
Location: NIH, Bethesda, MD
Learn more

Sirolimus in Eosinophilic GI Disease

Study Reference: NCT01814059
Location: National Institutes of Health Clinical Center, Bethesda, MD

Learn more


Eosinophilic Gastritis (EG)

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

Study Reference: NCT00267501
Location: Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Learn more

 


Eosinophilic Granulomatosis With Polyangitis (Churg Strauss Syndrome)

Determining Disease Activity Biomarkers in Individuals With Eosinophilic Granulomatosis With Polyangitis (Churg-Strauss Syndrome)

Study Reference: NCT00315380
Location: Please view the link below for the complete list of locations.

Learn more

Vasculitis Clinical Research Consortium Genetic Repository One-Time DNA Study

Study Reference: NCT01241305
Location: Please view the link below for the complete list of locations
.
Learn more 


HES (Hypereosinophilic Syndrome)
 

Compassionate Use of Mepolizumab in Subjects With Hypereosinophilic Syndrome

Study Reference: NCT00244686
Location: Please view the link below for the complete list of locations.
Learn more

Imatinib Mesylate to Treat Myeloproliferative Hypereosinophilic Syndrome

Study Reference: NCT00044304
Location: National Institutes of Health Clinical Center, Bethesda, MD
Learn more

Steroid Treatment for Hypereosinophilic Syndrome

Study Reference: NCT01524536
Location: National Institutes of Health Clinical Center, Bethesda, MD
Learn more


Vasculitis

American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic Vasculitis (DCVAS)

Study Reference: NCT01066208
Location:  Please view the link below for the complete list of locations.
Learn more

Hematopoietic Stem Cell Support in Vasculitis

Study Reference: NCT00278512
Location: Northwestern University, Feinberg School of Medicine, Chicago, IL
Learn more

One-Time DNA Study for Vasculitis

Study Reference: NCT01241305
Location: Please view the link below for the complete list of locations.
Learn more