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Grant Recipients

 

2015 Hope APFED/ARTrust™ Pilot Grant Award

The 2015 Hope APFED/ARTrust™ Pilot Grant Award is the result of a collaborative effort between APFED and the Allergy, Asthma & Immunology Education and Research Organization, Inc. (ARTrust™), and was established to allow investigators from a variety of disciplines to initiate new projects relevant to eosinophilic diseases, with a focus on the development of new ideas that are likely to lead to future external funding.

Please join us in congratulating the recipient of this year’s award, Dr. Antonella Cianferoni.

Antonella Cianferoni, MD, PhD
Assistant Professor of Pediatrics
Children’s Hospital of Philadelphia

Hope APFED/ARTrust™ Pilot Grant Award Amount: $140,000 over a 2-year period, co-funded between APFED and ARTrust™

 

Project:  Dr. Cianferoni’s project entitled “Genotype Phenotype Correlation in Eosinophilic Esophagitis” will help us better understand genetic variations in the development of EoE, and the important role that thymic stromal lymphopoietin (TSLP), a protein that promotes allergic inflammation, plays in the process.

Patient Impact: This research could potentially lead to a better understanding of the relationship between TSLP and two other regulator proteins (EMSY and CAPN14).

 

2015 HOPE Pilot Research Grant

APFED is proud to support the following HOPE Pilot Research Grant in 2015. Congratulations to Dr. Ting Wen for his grant-winning proposal. We look forward to his valuable contribution to eosinophilic disease research.

Ting Wen, Phd
Instructor of Pediatrics
Research Instructor in Pediatrics
Division of Allergy and Immunology

Cincinnati Children’s Hospital Medical Center, Burnet Campus

HOPE Pilot Grant Amount: $100,000 over a 2-year period

Project: Dr. Wen’s project entitled “Defining Esophageal Lymphocyte Phenotype and Function in Eosinophilic Esophagitis” seeks to provide a greater understanding of the heterogeneity of human intraepithelial lymphocytes (IELs) and their functionality in EoE.

Patient Impact:  The knowledge gained through this research could advance our understanding of the mechanisms of the enigmatic human IEL population, as well as EoE pathogenesis.

 

2014 Hope APFED/ARTrust™ Pilot Grant Award

The 2014 Hope APFED/ARTrust™ Pilot Grant Award is the result of a collaborative effort between APFED and the Allergy, Asthma & Immunology Education and Research Organization, Inc. (ARTrust™), and was established to allow investigators from a variety of disciplines to initiate new projects relevant to eosinophilic diseases, with a focus on the development of new ideas which are likely to lead to future external funding. Please join us in congratulating the recipient of this year's award, Dr. Michiko K. Oyoshi.

Michiko K. Oyoshi, PhD
Assistant Professor
Boston Children's Hospital
 

Hope APFED/ARTrust™ Pilot Grant Award Amount: $140,000 over a 2-year period, co-funded between APFED and ARTrust™

Project: “Mechanisms of Eosinophil Recruitment to Esophagitis Driven by Cutaneous Sensitization”Dr. Oyoshi’s research will focus on an innovative approach to define the underlying mechanism for the development of eosinophilic esophagitis (EoE)

Patient Impact: A better understand the role of eosinophols and their products, and how these play a part in EoE could lead to new treatments for the disease.

 

2014 HOPE Pilot Research Grant

APFED is proud to support the following HOPE Pilot Research Grant in 2014. Congratulations to Dr. Masterson for her grant-winning proposal. We look forward to her valuable contribution to eosinophil research.

Joanne Masterson, PhD
Instructor of Pediatrics
Gastrointestinal Eosinophilic Diseases Program
Digestive Health Institute
Children’s Hospital Colorado
Mucosal Inflammation Program
University of Colorado School of Medicine

HOPE Pilot Grant Amount: $50,000 for a 1-year period
Project: 
HIF signaling and mucosal healing in EoE

Dr. Masterson’s research will provide a greater understanding of the signaling pathway of certain cells involved with EoE as they relate to inflammation caused by oxygen deficiency in cells and tissue. Her research will help determine whether or not this signaling mediates a critical link between conditions that cause inflammation and how the mucosal tissue heals after it is damaged by EoE.

Patient Impact: Understanding the molecular mechanisms of HIF signaling pathway in EoE may lead to new ways to treat the disease. 

 

Letters of Appreciation - Researchers express gratitude for grants received through APFED's Hope on the Horizon Research Fund.