Clinical trials
Clinical trial participation is an individual, and important, decision. Clinical trials are designed to test new medications in people. Clinical trials may involve a placebo group (inactive ‘medicine’) to see if the new medication offers an advantage over current standard treatment. Some trials are ‘open label’, in which all participants receive active medications or experimental treatment.
There are many advantages to participating in clinical trials. Participants in clinical trials at a minimum receive current standard care for their disease from medical teams experienced with the disease. Clinical trials also offer the opportunity to try a new medication long before it is approved by the Food and Drug Administration.
If you choose to participate in a clinical trial, you have the right to understand fully what is expected of you, what the trial will involve and the potential risks to your health. You also have the right to withdraw your consent to participate at any time. Learn more about clinical trials, including those listed on this page, at www.clinicaltrials.gov.
The clinical trials listed here were verified as open and enrolling at the time the post was made, and are monitored periodically to ensure that the trial is still accepting participants. If a trial is no longer accepting patients, APFED may not be notified. If you find that registration has closed for a trial that is still listed on this page, please notify
mail@apfed.org.
Trials That May be of Interest to Our Members
Updated 8/22/14
Eosinophilic Colitis (EC)
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
Study Reference: NCT00267501
Location: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
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Eosinophilic Esophagitis (EoE)
Anti-IL-13 antibody (RPC4046) drug in Adults with EOE: A Phase II, Multi-Center, Multi-National, Randomized, Double-Blind, Placebo Controlled, Parallel Group Study
Study Reference: NCT02098473
Location: Please view the link below for the complete list of locations.
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Cytosponge Protocol
Study Reference: NCT01585103
Location: Mayo Clinic, Rochester MN
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Data and Sample Collection Study to Elucidat the Mechanisms of Eosinophilic Disorders
Study Reference: NCT00267501
Location: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
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Esophageal String Test in Eosinophilic Esophagitis
Study Reference: NCT02008903
Location: Children’s Hospital Colorado (Aurora, CO); Lurie Children’s Hospital (Chicago, IL); Northwestern University (Chicago, IL)
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Eosinophilic Esophagitis Clinical Therapy Trial
Study Reference: NCT01821898
Location: Texas Children’s Hospital, Houston, TX
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Eosinophilic Esophagitis Databank
Study Reference: NCT01323803
Location: Please view the link for the complete list of locations.
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Confocal Laser Endomicroscopy in Patients with Eosinophilic Esophagitis
Study Reference: NCT01234376
Location: University of Erlangen-Nuremberg, Erlangen, Bayern, Germany
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Development, Validation and Evaluation of an Adult and Pediatric Eosinophilic Esophagitis Activity Index (EEsAI)
Study Reference: NCT00939263
Location: Please view the link below for the complete list of locations.
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Dietetic Versus Topical Steroids for Pediatric Eosinophilic Esophagitis
Study Reference: NCT01846962
Location: Rome, Italy
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Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders
Study Reference: NCT01212016
Location: NIH, Bethesda, MD
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Intestinal Permeability in Response to Treatment in Eosinophilic Esophagitis Patients
Study Reference: NCT01641913
Location: Mayo Clinic, Rochester MN
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Molecular Basis of Food Allergy
Study Reference: 01832324
Location: Children’s Hospital of Philadelphia
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Mucosal Impedance and Eosinophilic Esophagitis
Study Reference: NCT01953575
Location: Mayo Clinic, Rochester MN
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Nasal Nitric Oxide Levels in EoE
Study Reference: NCT01929824
Location: Mayo Clinic, Rochester MN
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OBS (Oral Budesonide Suspension) in Adolescent and Young Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension
Study Reference: NCT01642212
Location: Please view the link below for the complete list of locations.
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Prevalence of Food Allergies in a Cohort of Adult Patients With Eosinophilic Esophagitis
Study Reference: NCT01631591
Location: University of South Florida, Tampa, FL
Risk Factors and Biomarkers for Diagnosis and Treatment of EoE
Study Reference: NCT01988285
Location: University of North Carolina, Chapel Hill NC
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Sirolimus in Eosinophilic GI Disease
Study Reference: NCT01814059
Location: National Institutes of Health Clinical Center, Bethesda, MD
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Study of the Efficiency of Esophageal Dilation on Patient With Eosinophilic Esophagitis (EOE)
Study Reference: NCT00880906
Location: Vanderbilt University Medical Center Department of Gastroenterology, Nashville, TN
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Testing Effectiveness of Losartan vs Placebo in Patients With EoE With or Without a CTD
Study Reference: NCT01808196
Location: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
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Trial of Montelukast in Eosinophilic Esophagitis
Study Reference: NCT00511316
Location: Mayo Clinic, Rochester, MN
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Eosinophilic Gastroenteritis (EGE)
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
Study Reference: NCT00267501
Location: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
Learn more
Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders
Study Reference: NCT01212016
Location: NIH, Bethesda, MD
Learn more
Sirolimus in Eosinophilic GI Disease
Study Reference: NCT01814059
Location: National Institutes of Health Clinical Center, Bethesda, MD
Learn more
Eosinophilic Gastritis (EG)
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
Study Reference: NCT00267501
Location: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
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Eosinophilic Granulomatosis With Polyangitis (Churg Strauss Syndrome)
Determining Disease Activity Biomarkers in Individuals With Eosinophilic Granulomatosis With Polyangitis (Churg-Strauss Syndrome)
Study Reference: NCT00315380
Location: Please view the link below for the complete list of locations.
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Vasculitis Clinical Research Consortium Genetic Repository One-Time DNA Study
Study Reference: NCT01241305
Location: Please view the link below for the complete list of locations.
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HES (Hypereosinophilic Syndrome)
Compassionate Use of Mepolizumab in Subjects With Hypereosinophilic Syndrome
Study Reference: NCT00244686
Location: Please view the link below for the complete list of locations.
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Imatinib Mesylate to Treat Myeloproliferative Hypereosinophilic Syndrome
Study Reference: NCT00044304
Location: National Institutes of Health Clinical Center, Bethesda, MD
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Steroid Treatment for Hypereosinophilic Syndrome
Study Reference: NCT01524536
Location: National Institutes of Health Clinical Center, Bethesda, MD
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Vasculitis
American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic Vasculitis (DCVAS)
Study Reference: NCT01066208
Location: Please view the link below for the complete list of locations.
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Hematopoietic Stem Cell Support in Vasculitis
Study Reference: NCT00278512
Location: Northwestern University, Feinberg School of Medicine, Chicago, IL
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One-Time DNA Study for Vasculitis
Study Reference: NCT01241305
Location: Please view the link below for the complete list of locations.
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