International Consensus Recommendations EGID Nomenclature

March 18, 2022

International consensus surrounding what subsets of eosinophilic gastrointestinal diseases (EGIDs) should now be called for both clinical and research purposes was recently published in the Journal of Gastroenterology and Hepatology.

Eosinophilic gastrointestinal disease (EGID) will continue be the umbrella term for eosinophilic inflammation in the GI tract when there is not another known cause.

The consensus indicated more specific terms should be used to describe has previously been called “eosinophilic gastroenteritis.”

These changes to the terms used to describe subsets of patients and conditions help characterize the specific areas of the GI tract that are affected. These include:

  • Eosinophilic Gastritis (EoG) = stomach
  • Eosinophilic Enteritis (EoN) = small bowel
  • Eosinophilic Colitis (EoC) = colon

“Eosinophilic Gastroenteritis” was previously used as a “catch-all” term for eosinophilia that was found in the stomach and/or small intestine, and should not be primarily used, with the terms above being used instead. The new international consensus also more granularly identifies areas of the GI tract that are affected:

  • Eosinophilic Duodenitis (EoD) = duodenum
  • Eosinophilic Jejunitis (EoJ) = jejunum
  • Eosinophilic Ileitis (EoI)  = ileum

This groundbreaking publication was spearheaded by CEGIR, a federally-funded research consortia in which APFED is a member.