Eosinophilic Gastritis Quick Facts

Eosinophilic Gastritis (EG)

Eosinophilic gastritis is a rare disease in which a type of white blood cell, the eosinophil, causes injury and inflammation to the stomach. Eosinophilic gastritis may affect both adults and children. The cause is unknown.


  • Vomiting, nausea
  • Difficulty feeding and/or gaining weight
  • Poor growth
  • Abdominal pain
  • Anemia (low blood counts)
  • Fatigue

Associated Diseases:

  • Environmental and/or food allergies in some
  • May occur in conjunction with other EGIDs


  • Unknown
  • Food allergies may play a role in some patients


  • Upper endoscopy (placement of a lighted tube into the mouth, esophagus and stomach)
  • Biopsies of the esophagus, stomach and small intestine are necessary to make the diagnosis. Eosinophils causing injury in the context of symptoms consistent with EG


  • Endoscopy may show erosions or irritated areas of the stomach
  • Biopsy: Eosinophils invading the stomach. Biopsy may show chronic inflammation. Eosinophils should be carefully sought when chronic inflammation is seen. No consensus recommendations on definition or diagnosis.
Allergy Testing

  • Allergy testing may be helpful in some patients to identify and remove offending food allergens.


  • Avoid known food allergens or triggers
  • Systemic Steroids (prednisone)
  • Elemental diet (avoid all food protein and obtain all nutrition from a special formula)
  • Iron supplementation if iron deficient


  • Depends on response to treatment
  • Recurrent episodes may occur

Author: Wendy Book MD, updated 9-08-2011, reviewed by Dr. Jonathan Markowitz
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